Role of Phyllanthus niruri on the modulation of stress and immune responses in Nile tilapia, Oreochromis niloticus

The use of nutraceuticals in aquaculture is getting attention to minimize oxidative stress and increase immunity of aquatic animals. In our experiment, we tested the potency of Phyllanthus niruri, as a stress-reducing and immune-stimulating agent in Nile tilapia, Oreochromis niloticus. We reared fis...

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Bibliographic Details
Published in:PloS one 2024-10, Vol.19 (10), p.e0309793
Main Authors: Ibrahim, Md, Khan, Mursalin, Mishu, Israt, Jahan, Ishrat, Mustafa, Ahmed
Format: Article
Language:English
Subjects:
Animal Feed - analysis
Animals
Antibiotics
Aquaculture
Aquaculture - methods
Aquatic animals
Biology and Life Sciences
Blood Glucose
Catecholamines
Cell size
Cichlids - immunology
Control
Defense mechanisms
Dietary Supplements
Fish
Food
Food and nutrition
Functional foods & nutraceuticals
Glucose
Health aspects
Hormones
Hydrocortisone - blood
Immune response
Immune system
Immunology
Immunomodulation
Lysozyme
Medicine and Health Sciences
Metabolism
Muramidase
Oreochromis niloticus
Oxidative stress
Pathogens
Phagocytes
Phagocytosis - drug effects
Phyllanthus
Phyllanthus - chemistry
Phyllanthus niruri
Physiological aspects
Physiology
Plant Extracts - pharmacology
Plasma
Plasma proteins
Recirculating systems
Regulation
Respiratory burst
Respiratory Burst - drug effects
Stress, Physiological - drug effects
Stress, Physiological - immunology
Tilapia
Vaccines
Varieties
Water quality
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Summary:The use of nutraceuticals in aquaculture is getting attention to minimize oxidative stress and increase immunity of aquatic animals. In our experiment, we tested the potency of Phyllanthus niruri, as a stress-reducing and immune-stimulating agent in Nile tilapia, Oreochromis niloticus. We reared fish in a recirculating system for 90 days at low (5 g/L) and high (30 g/L) densities. We fed half of the low and high-density fish with commercial feed (control feed) and the other half, with 5% Phyllanthus niruri incorporated into commercial feed (supplemented feed). We assessed plasma cortisol, blood glucose, packed cell volume, plasma proteins, phagocytic capacity, respiratory burst activity, and lysozyme activity. None of these parameters showed any significant difference among the experimental groups. Based on our findings, we conclude that Phyllanthus niruri does not have any potential role in modulating stress and immune response in fish as a nutraceutical.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0309793