Cortical encoding of phonetic onsets of both attended and ignored speech in hearing impaired individuals

• Published in: PloS one 2024-11, Vol.19 (11), p.e0308554
• Main Authors: Carta, Sara, Aličković, Emina, Zaar, Johannes, Valdés, Alejandro López, Di Liberto, Giovanni M
• Format: Article
• Language: English
• Subjects: Acoustic Stimulation; Acoustics; Adult; Aged; Attention; Attention - physiology; Auditory system; Background noise; Boundaries; Cerebral cortex; Coding; Comprehension; Datasets; EEG; Electrodes; Electroencephalography; Female; Health aspects; Hearing aids; Hearing disorders; Hearing impaired; Hearing loss; Hearing Loss - physiopathology; Humans; Hypotheses; Impairment; Listening; Male; Medical research; Medicine, Experimental; Middle Aged; Neural coding; Neurophysiology; Onset (Phonology); Phonemes; Phonetics; Phonology; Physiological aspects; Response functions; Sound; Speech; Speech - physiology; Speech Perception - physiology; Speech sounds; Streams
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0308554

Hearing impairment alters the sound input received by the human auditory system, reducing speech comprehension in noisy multi-talker auditory scenes. Despite such difficulties, neural signals were shown to encode the attended speech envelope more reliably than the envelope of ignored sounds, reflecting the intention of listeners with hearing impairment (HI). This result raises an important question: What speech-processing stage could reflect the difficulty in attentional selection, if not envelope tracking? Here, we use scalp electroencephalography (EEG) to test the hypothesis that the neural encoding of phonological information (i.e., phonetic boundaries and phonological categories) is affected by HI. In a cocktail-party scenario, such phonological difficulty might be reflected in an overrepresentation of phonological information for both attended and ignored speech sounds, with detrimental effects on the ability to effectively focus on the speaker of interest. To investigate this question, we carried out a re-analysis of an existing dataset where EEG signals were recorded as participants with HI, fitted with hearing aids, attended to one speaker (target) while ignoring a competing speaker (masker) and spatialised multi-talker background noise. Multivariate temporal response function (TRF) analyses indicated a stronger phonological information encoding for target than masker speech streams. Follow-up analyses aimed at disentangling the encoding of phonological categories and phonetic boundaries (phoneme onsets) revealed that neural signals encoded the phoneme onsets for both target and masker streams, in contrast with previously published findings with normal hearing (NH) participants and in line with our hypothesis that speech comprehension difficulties emerge due to a robust phonological encoding of both target and masker. Finally, the neural encoding of phoneme-onsets was stronger for the masker speech, pointing to a possible neural basis for the higher distractibility experienced by individuals with HI.