Cross-sectional study of lung cancer patients as a potential high-risk factor for abdominal aortic aneurysm

• Published in: PloS one 2025-01, Vol.20 (1), p.e0315898
• Main Authors: Gwon, Hye Ran, Woo, A La, Yong, Seung Hyun, Park, Young Mok, Kim, Song Yee, Kim, Eun Young, Jung, Ji Ye, Kang, Young Ae, Park, Moo Suk, Kang, Du-Young, Park, Seong Yong, Lee, Sang Hoon, Kwon, Jun Seong
• Format: Article
• Language: English
• Subjects: Abdomen; Abdominal aneurysm; Age; Aorta; Aortic aneurysms; Chronic obstructive pulmonary disease; Complications and side effects; Computed tomography; Coronary artery disease; Coronary vessels; Cross-sectional studies; Demographic aspects; Diagnosis; Ethics; Heart diseases; Hospitals; Hypertension; Life expectancy; Lung cancer; Lung cancer, Non-small cell; Lung diseases; Medical prognosis; Medicine and Health Sciences; Metabolic disorders; Mortality; Multivariable control; Non-small cell lung carcinoma; Regression analysis; Review boards; Risk factors; Small cell lung carcinoma; Smoking; Statistical analysis; Surgery; Surveillance; Survival analysis; Tomography
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0315898

Abdominal aortic aneurysm (AAA) is more common in Non-small cell lung cancer (NSCLC) patients. Considering that ruptured AAA is potentially fatal, timely management of AAA would result in long-term survival benefits. We assess the prevalence and characteristics of AAA in resectable NSCLC patients who would benefit from AAA surveillance. 1,019 resectable NSCLC patients in Severance and Kangbuk Samsung Hospitals were reviewed from January 2019 to November 2020. The control group comprised 2,899 cancer-free people who had a health check-up CT scan in Severance between January 2018 and December 2019. Among resectable primary NSCLC patients, 39/1,019 (3.8%; odds ratio [OR], 19.19; 95% confidence interval [CI], 8.10-46.46) had AAA compared with 6/2,899 (0.2%) in the control (P