Tetherless thermobiochemically actuated microgrippers

We demonstrate mass-producible, tetherless microgrippers that can be remotely triggered by temperature and chemicals under biologically relevant conditions. The microgrippers use a self-contained actuation response, obviating the need for external tethers in operation. The grippers can be actuated e...

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 2009-01, Vol.106 (3), p.703-708
Main Authors: Leong, Timothy G, Randall, Christina L, Benson, Bryan R, Bassik, Noy, Stern, George M, Gracias, David H
Format: Article
Language:English
Subjects:
Animals
Automation
Biochemistry
Biopsy
Biopsy - methods
Cattle
Cell culture techniques
Cell Survival
Cells
Cells, Cultured
Elasticity
Joints
Magnets
Mice
Phalanges
Physical Sciences
Polymers
Polymers - chemistry
Residual stress
Robotics
Silicon
Temperature
Thin films
Tissues
Ungulates
Urinary Bladder - pathology
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Summary:We demonstrate mass-producible, tetherless microgrippers that can be remotely triggered by temperature and chemicals under biologically relevant conditions. The microgrippers use a self-contained actuation response, obviating the need for external tethers in operation. The grippers can be actuated en masse, even while spatially separated. We used the microgrippers to perform diverse functions, such as picking up a bead on a substrate and the removal of cells from tissue embedded at the end of a capillary (an in vitro biopsy).
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.0807698106