Photo catalogue for the classification of foci in the BALB/c 3T3 cell transformation assay

► This photo catalogue describes the different types of foci in the BALB/c 3T3 CTA. ► This visual aid will support method transfer and consistency in focus scoring. ► It should be used with the protocol by laboratories that intend to run the assay. This catalogue is a display of focus photos represe...

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Bibliographic Details
Published in:Mutation research. Genetic toxicology and environmental mutagenesis 2012-04, Vol.744 (1), p.42-53
Main Authors: Sasaki, Kiyoshi, Bohnenberger, Susanne, Hayashi, Kumiko, Kunkelmann, Thorsten, Muramatsu, Dai, Poth, Albrecht, Sakai, Ayako, Salovaara, Susan, Tanaka, Noriho, Thomas, B. Claire, Umeda, Makoto
Format: Article
Language:English
Subjects:
BALB/c 3T3 cell line
Bioassays
Carcinogenicity
Cell transformation assay
Cells
Classification
Photo catalogue
Protocol
Transformed foci
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Summary:► This photo catalogue describes the different types of foci in the BALB/c 3T3 CTA. ► This visual aid will support method transfer and consistency in focus scoring. ► It should be used with the protocol by laboratories that intend to run the assay. This catalogue is a display of focus photos representative of the BALB/c 3T3 cell transformation assay (CTA). It is intended as a visual aid for the identification and the scoring of foci in the conduct of the assay. A proper training from experienced personnel together with the protocol reported in this issue and the present photo catalogue will support method transfer and consistency in the assay results.
ISSN:1383-5718
1879-3592
DOI:10.1016/j.mrgentox.2012.01.009