OR-30: Stress induced impaired pressure natriuresis is associated with an extended period of elevated blood pressure in black youths

Background: Blacks have a greater prevalence of hypertension and associated target organ damage than Whites. Salt and stress are two risk factors that have been associated with these differences. Hypothesis: Stress induced impaired sodium regulation results in an extended period of elevated blood pr...

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Bibliographic Details
Published in:American journal of hypertension 2002-04, Vol.15 (S3), p.14A-14A
Main Authors: Harshfield, Gregory A., Wilson, Martha E., Mackey, Lynne, Gillis, Delores, Treiber, Frank A., Hanevold, Coral D., Kapuku, Gaston K.
Format: Article
Language:English
Subjects:
Blood Presure
Race Differences
Sodium Regulation
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Summary:Background: Blacks have a greater prevalence of hypertension and associated target organ damage than Whites. Salt and stress are two risk factors that have been associated with these differences. Hypothesis: Stress induced impaired sodium regulation results in an extended period of elevated blood pressure in Blacks. The resulting increased cardiovascular load contributes to the premature development of hypertension in Blacks. Methods: Black youths (n=121; aged 15-18 years) were brought into similar levels of sodium balance. Sodium excretion (UNaV) and systolic blood pressure (SBP) were measured during a one hour stress period which was preceded and followed by two hour rest periods. The subjects were divided into two groups based on the direction of change in UNaV during the stress period: excrete (n = 82); and retain (n = 39). Results: The time by group interactions were significant for both variables (P
ISSN:0895-7061
1941-7225
DOI:10.1016/S0895-7061(02)02310-5