P-615: The role of glucozided haemoglobulin in the ambulatory blood pressure of hypertensive women

• Published in: American journal of hypertension 2003-05, Vol.16 (S1), p.261A-261A
• Main Authors: Papavasilioy, Maria V., Anadiotis, Athanasios V., Daskalakis, Cosmas V., Kelepouris, Panagiotis Ch, Thomopoulos, Konstantinos G.
• Format: Article
• Language: English
• Subjects: Glucozided Haemoglobin; Hypertensive Women
• ISSN: 0895-7061; 1941-7225
• DOI: 10.1016/S0895-7061(03)00788-X

Aim: The purpose of this study was to elucidate the association between glucozided haemoglobulin serum levels (HbA1c) and the levels of 24 hours monitoring blood pressure of premenopause and menopause hypertensive women. Methods: We studied 20 women with essential hypertension without any treatment (12 menopause women [medium] AGE =60.16±5.1 years old, [medium] SDBP=152.8/96.7±17.6/11.5 mmhg and 8 premenopause women [medium] age=39.5 ±12 years old, [medium] SDBP=144.8/99.8 ±7.1/2.3 mmhg).We measured serum HbA1c of the subjects and a 24 hours recording of blood pressure was achived. Results: There was a significant correlation between HbA1c and office SBP(r=0.512 p=0.05), night SBP (r=0.580 p=0.048), as well as with 24 hours systolic pressure load: SBP24R (r=0.615 p=0.044) in menopause hypertensive women and a significant correlation between HbA1c and office DBP (r=0.825 p=0.001) day DBP (r=-0.901 p=0.0060, [medium] 24 DBP (r=-0.953 p=0.001), [medium] office BP (r=0.807 p=0.001) in premenopause hypertensive women. Conclusions: HbA1c is significant correlated with hypertensive status of women and particular in premenopause hypertensive women, suggesting the relationship between glucose and blood pressure.