Profiling of impurities in p-methoxymethamphetamine (PMMA) by means of SPE/TLC method examination of the influence of experimental conditions according to 24 factorial

In the present paper profiling of impurities in p -methoxymethamphetamine (PMMA) by means of SPE/TLC is reported. PMMA was synthesised by Leuckart procedure. The influence of experimental conditions on the profile quality was investigated. The experiments were carried out according to a 24 factorial...

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Bibliographic Details
Published in:Forensic science international 2003, Vol.134 (2-3), p.214-218
Main Authors: KOCHANA, J, WILAMOWSKI, J, PARCZEWSKI, A
Format: Article
Language:English
Subjects:
Aqueous solutions
Biological and medical sciences
Chromatography
Drug addictions
Ethanol
Forensic sciences
Fourier transforms
Medical sciences
Methods
Studies
Toxicology
Online Access:Get full text
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Summary:In the present paper profiling of impurities in p -methoxymethamphetamine (PMMA) by means of SPE/TLC is reported. PMMA was synthesised by Leuckart procedure. The influence of experimental conditions on the profile quality was investigated. The experiments were carried out according to a 24 factorial. The proposed characteristics of the profile quality (optimisation criterions) are based on a matrix presentation of TLC patterns. They take into account, simultaneously, the number of spots revealed, differences between R f values and intensity of fluorescence.
ISSN:0379-0738
1872-6283
DOI:10.1016/S0379-0738(03)00162-2