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Micro RNA: New aspect in pathobiology of preeclampsia?

The discovery of miRNA in 1993, by Ambros et al. has had a huge influence in pathogenesis theory; diagnosis and treatment approach to some diseases. Some scientifically proven theories have been proposed to seek the association of alterations of miRNA expression to incidences and severity of preecla...

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Bibliographic Details
Published in:The Egyptian journal of medical human genetics 2012-06, Vol.13 (2), p.127-131
Main Authors: Harapan, Harapan, Andalas, Mohd, Mudhakir, Diky, Pedroza, Natalia C., Laddha, Saurabh V, Anand, Jay R.
Format: Article
Language:English
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Summary:The discovery of miRNA in 1993, by Ambros et al. has had a huge influence in pathogenesis theory; diagnosis and treatment approach to some diseases. Some scientifically proven theories have been proposed to seek the association of alterations of miRNA expression to incidences and severity of preeclampsia (PE). In this review we explore the result of such investigations that discuss the association of miRNA and PE along with the role of various mRNAs in PE pathogenesis.
ISSN:1110-8630
2090-2441
DOI:10.1016/j.ejmhg.2011.09.002