Clinical Use of Tolterodine Extended Release in Overactive Bladder

Overactive bladder (OAB) is a common problem whose prevalence increases with advancing age and compromises health-related quality of life. Tolterodine was the first antimuscarinic drug specifically designed to treat OAB. Through MEDLINE, we reviewed articles, standardization reports and meeting abst...

Full description

Saved in:
Bibliographic Details
Published in:Clinical Medicine Insights: Urology 2012-04, Vol.2012 (2012), p.1-9
Main Authors: Adli, Oussama El Yazami, Corcos, Jacques
Format: Article
Language:English
Subjects:
Drug therapy
Health aspects
Urinary incontinence
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Overactive bladder (OAB) is a common problem whose prevalence increases with advancing age and compromises health-related quality of life. Tolterodine was the first antimuscarinic drug specifically designed to treat OAB. Through MEDLINE, we reviewed articles, standardization reports and meeting abstracts, published between 2001 and 2011, on the efficacy and tolerability of Tolterodine extended release (ER). Our search terms included Tolterodine, extended release, overactive bladder, therapeutic use, efficacy, tolerance, and adverse events. Tolterodine ER, via steady drug release during the daytime, gives the benefit of constant serum concentration and thus better efficacy and tolerability in comparison to Tolterodine immediate release, even in elderly patients with co-morbid conditions.
ISSN:1179-5611
1179-5611
DOI:10.4137/CMU.S6425