Highly aggressive buschke-löwenstein tumor of the perineal region with fatal outcome

[...]due to pain, pus-like discharge, bleeding, and intolerable fetid odour, the patient was forced to come to the hospital. In analysis of 42 cases reported in the literature, Chu et al. found 66% recurrence rate and transformation into squamous cell carcinoma in 55% of cases with overall mortality...

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Bibliographic Details
Published in:Indian journal of dermatology, venereology, and leprology venereology, and leprology, 2012-09, Vol.78 (5), p.648, Article 648
Main Authors: Radovanovic, Zoran, Radovanovic, Dragana, Semnic, Robert, Nikin, Zoran, Petrovic, Tomislav, Kukic, Biljana
Format: Article
Language:English
Subjects:
Buschke-Lowenstein Tumor - complications
Buschke-Lowenstein Tumor - pathology
Buschke-Lowenstein Tumor - surgery
Care and treatment
Chemoradiotherapy
Chemotherapy
Colostomy
Diagnosis
Fatal Outcome
Hospitals
Humans
Male
Middle Aged
Mortality
Neoplasm Invasiveness
Neoplasm Recurrence, Local - therapy
Papillomavirus infections
Perineum
Physiological aspects
Radiation therapy
Sepsis - etiology
Skin Neoplasms - complications
Skin Neoplasms - pathology
Skin Neoplasms - surgery
Skin tumors
Surgery
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Summary:[...]due to pain, pus-like discharge, bleeding, and intolerable fetid odour, the patient was forced to come to the hospital. In analysis of 42 cases reported in the literature, Chu et al. found 66% recurrence rate and transformation into squamous cell carcinoma in 55% of cases with overall mortality of 20% (all occurring in patients with recurrence). Some other modalities are often used like: cryosurgery, CO 2 laser surgery, podophyllin, intralesional bleomycin, 13-cis retinoic acid, systemic chemotherapy, topical 5-FU, imiquimod, and interferon-α.
ISSN:0378-6323
0973-3922
1998-3611
DOI:10.4103/0378-6323.100584