Synthesis and X-ray crystal structure analysis of 4-(3,4-dichlorophenyl)-2-(3,4,5-trimethoxy-benzylidene)-3,4-dihydro-naphthalen-1(2 H )-one: Sertraline key intermediate analog

The novel bioactive compound 4-(3,4-dichlorophenyl)-2-(3,4,5-trimethoxy-benzylidene)-3,4-dihydro-naphthalen-1(2 H)-one was synthesised in three different methods, namely, conventional, MW irradiation with solvent and MW irradiation without solvent. The synthesised compound was characterised by spect...

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Published in:Journal of chemical research 2006-11, Vol.2006 (11), p.730-732
Main Authors: Kavitha, Chandagirikoppal V., Mantelingu, Kempegowda, Sarala, Gangadaraiah, Naveen, S., Anandalwar, Sridhar M., Prasad, Javaregowda Shashidhara, Rangappa, Kanchugarakoppal S.
Format: Article
Language:English
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Summary:The novel bioactive compound 4-(3,4-dichlorophenyl)-2-(3,4,5-trimethoxy-benzylidene)-3,4-dihydro-naphthalen-1(2 H)-one was synthesised in three different methods, namely, conventional, MW irradiation with solvent and MW irradiation without solvent. The synthesised compound was characterised by spectroscopic techniques and finally confirmed by X-ray crystal structure analysis.
ISSN:1747-5198
2047-6507
DOI:10.3184/030823406779173271