Sulfamic Acid Catalysed One-Pot Three-Component Condensation for the Synthesis of 1,4-dihydropyrano[2,3- c ]pyrazoles

A clean and simple synthesis of 6-amino-4-aryl-3-methyl-1-phenyl-1,4-dihydropyrano[2,3- c]pyrazole-5-carbonitriles was accomplished in good to excellent yields via the one-pot three component condensation of 3-methyl-1-phenyl-2-pyrazolin-5-one, an aromatic aldehyde, and malononitrile catalysed by su...

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Bibliographic Details
Published in:Journal of chemical research 2008-05, Vol.2008 (5), p.278-279
Main Authors: Shinde, Sandeep V., Jadhav, Wamanrao N., Kondre, Jeevan M., Gampawar, Sumit V., Karade, Nandkishor N.
Format: Article
Language:English
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Summary:A clean and simple synthesis of 6-amino-4-aryl-3-methyl-1-phenyl-1,4-dihydropyrano[2,3- c]pyrazole-5-carbonitriles was accomplished in good to excellent yields via the one-pot three component condensation of 3-methyl-1-phenyl-2-pyrazolin-5-one, an aromatic aldehyde, and malononitrile catalysed by sulfamic acid in ethanol.
ISSN:1747-5198
2047-6507
DOI:10.3184/030823408X321051