Diagnosis of peritoneal metastases with abdominal malignancies: role of ADC measurement on diffusion weighted MRI/Abdominal malignansilerin peritoneal metastazlarinin tanisinda difuzyon agirlikli MRG'de gorunur difuzyon katsayisi olcumunun rolu

• Published in: The Eurasian journal of medicine 2012-12, Vol.44 (3), p.163
• Main Authors: Onur, Mehmet Ruhi, Akyol, Muammer, Poyraz, Ahmet Kursad, Kocakoc, Ercan, Ogur, Erkin
• Format: Article
• Language: English
• Subjects: Abdomen; Diagnosis; Diffusion; Digestive system cancer; Magnetic resonance imaging; Metastasis; NMR; Nuclear magnetic resonance; Patients; Tomography; Tumors
• ISSN: 1308-8734; 1308-8742
• DOI: 10.5152/eajm.2012.38

Objective: The purpose of our study was to evaluate the utility of the apparent diffusion coefficient (ADC) value measurement in the diagnosis of peritoneal metastases on diffusion weighted magnetic resonance imaging. Materials and Methods: Diffusion weighted imaging with conventional magnetic resonance imaging sequences was performed on twenty consecutive oncology patients (group I) with peritoneal metastases. The ADC values of the metastases, the peritoneal fat around the metastases (group I) and the peritoneal fat in patients with no malignancy (group II) at b(0-100), b(0-600), and (b 0-1000) s/mm2gradients were measured and compared. Results: The apparent diffusion coefficient values of three gradients in peritoneal metastases (2.27±0.4; 1.67±0.7 and 1.09±0.4 x [10.sup.-3] [mm.sup.2]/s at b 100, 600 and 1000 gradients, respectively) were significantly lower than the ADC values of the peritoneal fat around metastases (3.07±0.4; 2.07±0.4; 1.33±0.3 x [10.sup.-3] [mm.sup.2]/s at b 100, 600 and 1000 gradients, respectively) (p0.05). Conclusion: The measurement of ADC values may be used as a complementary diagnostic method in differentiating peritoneal metastases from peritoneal fat on Diffusion Weighted MRI (DWMRI DWMRI). Key Words: Apparent diffusion coefficient value, Diffusion weighted imaging, Malignancy, Metastasis, Peritoneum Amac: Bu calismanin amaci difuzyon agirlikli manyetik rezonans goruntulemede (MRG) peritoneal metastazlarin tanisinda gorunur difuzyon katsayisi (ADC) degerlerinin yararliligini degerlendirmektir. Gerec ve Yontem: Peritoneal metastazi bulunan 20 onkoloji hastasina (grup 1) konvansiyonel MRG sekanslari ile birlikte difuzyon agirlikli goruntuleme gerceklestirildi. Peritoneal metastazlarin, metastaz cevresindeki yag dokusunun ve malignansisi olmayanlarin (grup 2) peritoneal yag dokusunun ADC degerleri b (0-100), b (0-600), and (b 0-1000) s/mm2 difuzyon gradiyentlerinde olculdu ve karsilastirildi. Bulgular: Peritoneal metastazlarin 3 gradientte elde edilen ADC degerleri (b 100, 600 and 1000 gradientlerinde sirasiyla 2.27±0.4; 1.67±0.7 and 1.09±0.4 x [10.sup.-3] [mm.sup.2]/s), metastaz cevresindeki yag dokusunun ADC degerlerinden (b 100, 600 and 1000 gradientlerinde sirasiyla 3.07±0.4; 2.07±0.4; 1.33±0.3 x [10.sup.-3] [mm.sup.2]/s) anlamli olarak dusuktur (p