Hypoglycemic Effect of Laminaria japonicaPolysaccharide in a Type 2 Diabetes Mellitus Mouse Model

The aim is to investigate the hypoglycemic effect of Laminaria japonicapolysaccharides (LJPS) on type 2 diabetes mellitus (T2DM) mice model. 60 healthy male mice have been used in the experiment. T2DM animal mode was prepared by high fatty forage feeding and intraperitoneal injection with alloxan. D...

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Bibliographic Details
Published in:ISRN endocrinology 2012-01
Main Authors: Li, Xiaodan, Yu, Zhuqin, Long, Shaohua, Guo, Yunliang, Duan, Delin
Format: Article
Language:English
Subjects:
Diabetes
Hyperglycemia
Insulin
Insulin resistance
Metabolic disorders
Rodents
Studies
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Summary:The aim is to investigate the hypoglycemic effect of Laminaria japonicapolysaccharides (LJPS) on type 2 diabetes mellitus (T2DM) mice model. 60 healthy male mice have been used in the experiment. T2DM animal mode was prepared by high fatty forage feeding and intraperitoneal injection with alloxan. Diabetic mice were orally supplied with LJPS. Then their blood was collected for various biomedical measurements of fasting blood glucose (FBG), serum insulin, and amylin. Treatment with LJPS significantly reduced fasting blood glucose ( P
ISSN:2090-4630
2090-4649
DOI:10.5402/2012/507462