Effect of ultralow doses of thyroliberin on microviscosity of lipid components of biological membranes

Effects of the regulatory peptide thyroliberin on microviscosity of lipid components of endoplasmic reticulum biological membranes in mouse hepatocytes were studied by electron paramagnetic resonance. Thyroliberin in a concentration of 10^sup -3^-10^sup -18^ M decreased microviscosity of surface lay...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2000-01, Vol.129 (1), p.30-32
Main Authors: Bogdanova, N. G., Lelekova, T. V., Pal'mina, N. P.
Format: Article
Language:English
Subjects:
Membranes
Proteins
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Summary:Effects of the regulatory peptide thyroliberin on microviscosity of lipid components of endoplasmic reticulum biological membranes in mouse hepatocytes were studied by electron paramagnetic resonance. Thyroliberin in a concentration of 10^sup -3^-10^sup -18^ M decreased microviscosity of surface layers of membrane lipids. This decrease was the most pronounced (30%) under effects of 10^sup -10^ and 10^sup -16^ M thyroliberin. Physiological effects of thyroliberin corresponded to its influence on the membrane structure.[PUBLICATION ABSTRACT]
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02433860