Effect of the carotid body excision on the development of corazol-induced seizures

Bilateral glomectomy in albino rats produced protective effect against the development of corazol seizures, which was manifested in prolonged latency of seizures and a 2-fold shortening of their total duration. Acute hypoxia led to shortening of the latency both in glomectomized and in sham-operated...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 1998-09, Vol.126 (3), p.876-877
Main Authors: Agadzhanyan, N. A., Torshin, V. I., Shevchenko, L. V., Elfimov, A. I.
Format: Article
Language:English
Subjects:
Rodents
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Summary:Bilateral glomectomy in albino rats produced protective effect against the development of corazol seizures, which was manifested in prolonged latency of seizures and a 2-fold shortening of their total duration. Acute hypoxia led to shortening of the latency both in glomectomized and in sham-operated rats and significantly decreased the number of seizures in glomectomized rats, although a similar decrease in sham-operated rats was insignificant. Possible participation of sinocarotid reflexogenic zones in hypoxic protection against experimental seizures is discussed.[PUBLICATION ABSTRACT]
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02447362