Central circulation in rats with different tolerance to acute blood loss

Study of the dynamics of cardiac output in rats with different tolerance to acute massive blood loss showed that the pumping ability of the heart remains intact during the entire posthemorrhagic period in all high-resistant and in 65% low-resistant rats. In 35% rats that were low-resistant to blood...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 1998-10, Vol.126 (4), p.983-987
Main Authors: Kovalenko, N. Ya, Matsievskii, D. D., Arkhipenko, Yu. V.
Format: Article
Language:English
Subjects:
Medical treatment
Rodents
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Summary:Study of the dynamics of cardiac output in rats with different tolerance to acute massive blood loss showed that the pumping ability of the heart remains intact during the entire posthemorrhagic period in all high-resistant and in 65% low-resistant rats. In 35% rats that were low-resistant to blood loss, the cardiac output deficiency syndrome developed after cessation of bleeding against the background fall in arterial pressure and a decrease in the hepatic blood flow, which are the signs of rapid variant of the dysfunction produced by acute blood loss.[PUBLICATION ABSTRACT]
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02447298