Alcohol and Mortality in Busselton, Western Australia

The authors analyzed 23-year mortality (1966–1989) in 2,171 subjects aged ≥40 years from a Busselton, Western Australia, prospective study. The analysis revealed significant inverse associations between alcohol consumption and mortality, with trends of decreasing mortality shown from nondrinkers to...

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Bibliographic Details
Published in:American journal of epidemiology 1993-01, Vol.137 (2), p.242-248
Main Authors: Cullen, Kevin J., Knuiman, Matthew W., Ward, Nicholas J.
Format: Article
Language:English
Subjects:
Adult
alcohol drinking
Alcohol Drinking - adverse effects
Alcohol Drinking - epidemiology
Alcoholism - complications
Alcoholism - epidemiology
Alcoholism and acute alcohol poisoning
Biological and medical sciences
Cardiovascular Diseases - etiology
Cardiovascular Diseases - mortality
Cause of Death
Comorbidity
coronary disease
Diabetes Complications
Female
Follow-Up Studies
Forced Expiratory Volume
Health Surveys
Humans
Male
Medical sciences
Middle Aged
mortality
Proportional Hazards Models
Risk Factors
Smoking - adverse effects
Toxicology
Tropical medicine
Uric Acid - blood
Western Australia - epidemiology
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Summary:The authors analyzed 23-year mortality (1966–1989) in 2,171 subjects aged ≥40 years from a Busselton, Western Australia, prospective study. The analysis revealed significant inverse associations between alcohol consumption and mortality, with trends of decreasing mortality shown from nondrinkers to mild drinkers to moderate drinkers. Compared with nondrinkers, moderate drinkers had an adjusted relative risk of death due to all causes of 0.76 (95% confidence interval (CI) 0.61–0.94). The adjusted relative risk of cardiovascular disease death among moderate drinkers was 0.68 (95% CI 0.51–0.91), and that of coronary heart disease death was 0.66 (95% CI 0.45–0.98). Adjustment for baseline coronary disease risk factors strengthened these trends in the relative risks observed in both women and men. Baseline and follow-up data suggested that 87% of the nondrinkers were long-term abstainers, with 77% having been such for a lifetime. Am J Epidemiol 1993:137:242–8.
ISSN:0002-9262
1476-6256
DOI:10.1093/oxfordjournals.aje.a116665