Photodynamic therapy in the treatment of CSCR

Purpose To evaluate the efficacy of photodynamic therapy (PDT) to treat chronic central serous chorioretinopathy (CSC) and changes in neural retina (NR) thickness and best corrected visual acuity (BCVA) induced by PDT. Methods Non randomized, multicentric, interventional case series. 82 eyes of 72 p...

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Bibliographic Details
Published in:Acta ophthalmologica (Oxford, England) England), 2012-09, Vol.90 (s249), p.0-0
Main Author: RUIZ MORENO, JM
Format: Article
Language:English
Subjects:
Cancer
Ophthalmology
Photodynamic therapy
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Summary:Purpose To evaluate the efficacy of photodynamic therapy (PDT) to treat chronic central serous chorioretinopathy (CSC) and changes in neural retina (NR) thickness and best corrected visual acuity (BCVA) induced by PDT. Methods Non randomized, multicentric, interventional case series. 82 eyes of 72 patients with chronic CSC were treated by conventional PDT. LogMAR BCVA and central foveal thickness (CFT) measured by optical coherence tomography (OCT) before and after PDT, number of PDT treatments and complications were considered as outcome indicators. In 26 eyes LogMAR BCVA and OCT were evaluated before treatment and one year after PDT. 24 eyes from 24 patients with non chronic, non PDT treated forms of CSC were evaluated as a control group. Results BCVA changed from 0.53 before PDT to 0.48 at 6 months (p=0.007). Subretinal fluid disappeared in all the cases. CFT decreased from 325 µm, to 229 µm one month after PDT; to 206 µm at three months; and to 202µm at six months (p
ISSN:1755-375X
1755-3768
DOI:10.1111/j.1755-3768.2012.3214.x