KG-60-Piperazine as a New Heterogeneous Catalyst for Gewald Three-Component Reaction

Piperazine supported on amorphous silica (KG-60-piperazine) as a basic catalyst acts in the Gewald three-component reaction of some aldehydes and ketones with malononitrile as well as ethyl cyanoacetate. The catalyst shows general utility with a variety of starting carbonyl compounds. Moreover, the...

Full description

Saved in:
Bibliographic Details
Published in:Synthetic communications 2013-07, Vol.43 (13), p.1859-1864
Main Authors: Rezaei-Seresht, Esmail, Tayebee, Reza, Yasemi, Mohammad
Format: Article
Language:English
Subjects:
2-Aminothiophenes
Gewald reaction
heterogeneous catalysis
multicomponent reaction
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Piperazine supported on amorphous silica (KG-60-piperazine) as a basic catalyst acts in the Gewald three-component reaction of some aldehydes and ketones with malononitrile as well as ethyl cyanoacetate. The catalyst shows general utility with a variety of starting carbonyl compounds. Moreover, the catalyst can be reused for four additional cycles without significant loss of the activity. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications® to view the free supplemental file.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397911.2012.674607