Moderate alcohol consumption predicts long-term mortality in elderly subjects with chronic heart failure

OBJECTIVE: Moderate alcohol consumption is related to a reduction of mortality. However, this phenomenon is not well established in the elderly, especially in the presence of chronic heart failure (CHF). The aim of the study was to verify the effect of moderate alcohol consumption on 12-year mortali...

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Bibliographic Details
Published in:The Journal of nutrition, health & aging health & aging, 2013, Vol.17 (5), p.480-485
Main Authors: Gargiulo, G, Testa, G, Cacciatore, F, Mazzella, F, Galizia, G, Della-Morte, D, Langellotto, A, Pirozzi, G, Ferro, G, Ferrara, N, Rengo, F, Abete, Pasquale
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Aging
Alcohol
Alcohol Drinking - mortality
alcoholic beverages
Biological and medical sciences
Cardiology. Vascular system
Chronic Disease
Cognitive ability
Edema
elderly
Ethanol - administration & dosage
Ethanol - adverse effects
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Geriatrics/Gerontology
Heart
Heart failure
Heart Failure - mortality
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Humans
Italy - epidemiology
Male
Medical sciences
Medicine
Medicine & Public Health
Mortality
Neurosciences
Nutrition
Older people
Primary Care Medicine
Proportional Hazards Models
Quality of Life Research
regression analysis
risk
Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Summary:OBJECTIVE: Moderate alcohol consumption is related to a reduction of mortality. However, this phenomenon is not well established in the elderly, especially in the presence of chronic heart failure (CHF). The aim of the study was to verify the effect of moderate alcohol consumption on 12-year mortality in elderly community-dwelling with and without CHF. SETTINGS: community-dwelling from 5 regions of Italy. PARTICIPANTS: A cohort of 1332 subjects aged 65 and older. MEASUREMENT: Mortality after 12-year follow-up in elderly subjects (≥65 years old) with and without CHF was studied. Moderate alcohol consumption was considered ≤250 ml/day (drinkers). RESULTS: In the absence of CHF (n=947), mortality was 42.2% in drinkers vs. 53.7% in non-drinker elderly subjects (p=0.021). In contrast, in the presence of CHF (n=117), mortality was 86.5% in drinkers vs. 69.7% in non-drinker elderly subjects (p=0.004). Accordingly, Cox regression analysis shows that a moderate alcohol consumption is protective of mortality in the absence (HR=0.79; CI 95% 0.66–0.95; p
ISSN:1279-7707
1760-4788
DOI:10.1007/s12603-012-0430-4