Lipid Profile, Aip And Glycated Haemoglobin Level In Type-2 Diabetic Patients In Enugu, South-East Nigeria

Impaired lipid metabolism resulting from uncontrolled hyperglycaemia has been implicated in diabetes and glycated haemoglobin (HbA1c) used as predictor of uncontrolled hyperglycaemia. The present study is aimed at analyzing the HbA1c level, lipid profile and atherogenic index of plasma (AIP), in typ...

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Bibliographic Details
Published in:Journal of Asian scientific research (Online) 2012-05, Vol.2 (5), p.300
Main Authors: E, Neboh Emeka, J, Ikekpeazu Ebele, C, Maduka Ignatius, O, Aduba, M, Ibegbu Daniel, O, Aniagolu Miriam, E, Ezeike Benjamin
Format: Article
Language:English
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Summary:Impaired lipid metabolism resulting from uncontrolled hyperglycaemia has been implicated in diabetes and glycated haemoglobin (HbA1c) used as predictor of uncontrolled hyperglycaemia. The present study is aimed at analyzing the HbA1c level, lipid profile and atherogenic index of plasma (AIP), in type-2 diabetics in Enugu. Ninety (90) type-2 diabetic patients (46 males and 44 females) drawn from the diabetic clinic and 40 apparently-healthy, non-diabetics (20 males and 20 females), all aged 45-70 years, were included in the study. Venous blood samples were collected from the subjects after 8 hours fasting and analyzed for HbA1c, fasting blood glucose (FBG), total cholesterol (TC), triacylglycerol (TG) and high-density lipoprotein (HDL-C), whereas low-density lipoprotein (LDL-C), very low-density lipoprotein (VLDL-C) and AIP were calculated using standard procedures. Data was analyzed with SPSS computer software version 11 using student's t-test at 95% confidence limit. The results showed significant increase (P
ISSN:2226-5724
2223-1331