Immunohistochemical study of expression of Caveolin-1 in canine malignant mammary tumour

Caveolin-1 (Cav-1) is thought to have an important impact on both signal transduction and the mediation of intracellular processes and may contribute to certain steps of carcinogenesis in various types of cancer. Cav-1 immunohistochemical expression was studied in 37 canine malignant mammary tumours...

Full description

Saved in:
Bibliographic Details
Published in:Comparative clinical pathology 2013-09, Vol.22 (5), p.971-976
Main Authors: Golshahi, Hannaneh, Tavasoli, Abbas, Rezaie, Annahita, Farhadi, Mohammad
Format: Article
Language:English
Subjects:
Hematology
Medicine
Medicine & Public Health
Oncology
Original Article
Pathology
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Caveolin-1 (Cav-1) is thought to have an important impact on both signal transduction and the mediation of intracellular processes and may contribute to certain steps of carcinogenesis in various types of cancer. Cav-1 immunohistochemical expression was studied in 37 canine malignant mammary tumours to investigate the relationship of histopathological type and histopathologic grade with the expression of Cav-1. Cav-1 was expressed by epithelial cells in 33 of 37 (89.2 %) malignant mammary tumours. There was a significant relationship between epithelial expression of Cav-1 and histological grade of tumours ( P  
ISSN:1618-5641
1618-565X
DOI:10.1007/s00580-012-1511-9