Albumin/Creatinine Clearance Ratio as a Screening Test for Microalbuminuria in Diabetic Patients

One hundred consecutive insulin-treated diabetic patients with a normal serum creatinine value admitted to a Diabetes Day Care Unit were investigated. Because we were studying microalbuminuria, 20 patients with persistently positive Albustix tests had to be excluded. The albumin/creatinine clearance...

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Bibliographic Details
Published in:Journal of Clinical Biochemistry and Nutrition 1987, Vol.2(3), pp.195-201
Main Authors: JERNTORP, P., SUNDKVIST, G., JEPPSSON, J.-O.
Format: Article
Language:English
Subjects:
albumin/creatinine clearance ratio
blood pressure
diabetes mellitus
HbA1c
microalbuminuria
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Summary:One hundred consecutive insulin-treated diabetic patients with a normal serum creatinine value admitted to a Diabetes Day Care Unit were investigated. Because we were studying microalbuminuria, 20 patients with persistently positive Albustix tests had to be excluded. The albumin/creatinine clearance ratio, a test used to determine albuminuria in renal diseases since 1973, determines the loss of albumin from the total glomerular surface and has, in contrast to other methods for measurement of microalbuminuria, the advantage of being uninfluenced by diuresis. The albumin/creatinine clearance ratio, in comparison with random urinary albumin concentration, correlated well with 24-h urinary albumin excretion (r=0.74, p
ISSN:0912-0009
1880-5086
DOI:10.3164/jcbn.2.195