Effect of Sialoadenectomy on the Level of Circulating Mouse Epidermal Growth Factor (mEGF) and on the Reproductive Function in Male Mice

Levels of mouse epidermal growth factor (mEGF) in mouse plasma were measured by a sensitive two-site enzyme immunoassay (EIA) to study whether sialoadenectomy (removal of submaxillary gland) affects the level of the factor in the circulation. mEGF levels in plasma of sialoadenectomized mice were low...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Clinical Biochemistry and Nutrition 1988, Vol.5(3), pp.221-229
Main Authors: TOKIDA, Noriaki, SHINODA, Ichizo, KUROBE, Masayuki, TATEMOTO, Yukihiro, MORI, Masahiko, HAYASHI, Kyozo
Format: Article
Language:English
Subjects:
circulation
enzyme immunoassay
epidermal growth factor
fertility rate
sialoadenectomy
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c451t-8a92af133d98ac48d80fc3db0d375466b3612e3d5ec13b4b42c005054e0198243
cites
container_end_page 229
container_issue 3
container_start_page 221
container_title Journal of Clinical Biochemistry and Nutrition
container_volume 5
creator TOKIDA, Noriaki
SHINODA, Ichizo
KUROBE, Masayuki
TATEMOTO, Yukihiro
MORI, Masahiko
HAYASHI, Kyozo
description Levels of mouse epidermal growth factor (mEGF) in mouse plasma were measured by a sensitive two-site enzyme immunoassay (EIA) to study whether sialoadenectomy (removal of submaxillary gland) affects the level of the factor in the circulation. mEGF levels in plasma of sialoadenectomized mice were lower than those of sham-operated (operated without removal of submaxillary gland) mice, but the difference was not remarkable. That is, the submaxillary gland is not the sole source of EGF in the mouse body. Though the reproductive ability of normal male mice and of those sialoadenectomized or sham-operated was also studied, no significant difference in fertility rate of the mated female mice was found among them. Thus the EGF in submaxillary gland seems not to play important roles in male reproductive function of the mice.
doi_str_mv 10.3164/jcbn.5.221
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1441875993</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3098776521</sourcerecordid><originalsourceid>FETCH-LOGICAL-c451t-8a92af133d98ac48d80fc3db0d375466b3612e3d5ec13b4b42c005054e0198243</originalsourceid><addsrcrecordid>eNo9kM9qGzEQxkVIIE6aS59A0EtbWFdaSWvtsTVrp2ATSNKz0EqzscxacrVal7xBH7tynPowzAzfb_7wIfSRkimjFf-2Na2fimlZ0gs0oVKSQhBZXaIJqWlZEELqa3QzDFtCeCUqPkF_m64Dk3Do8JPTfdAWfO7D7hUHj9MG8AoO0B_1uYtm7HVy_gWvwzgAbvbOQtzpHi9j-JM2eKHzaMSfd81y8QVrb_8veYR9DHY0yR0AL0afi6w4j9e6B7x2Bj6gq073A9y951v0a9E8z--L1cPy5_z7qjBc0FRIXZe6o4zZWmrDpZWkM8y2xLKZ4FXVsoqWwKwAQ1nLW14aQgQRHAitZcnZLfp02psf-j3CkNQ2jNHnk4pyTuVM1DXL1NcTZWIYhgid2ke30_FVUaKOTquj00qo7HSGf5zg7ZD0C5xRHZMzPbyh-XiVcfYWeegsmo2OCjz7B4VeiLY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1441875993</pqid></control><display><type>article</type><title>Effect of Sialoadenectomy on the Level of Circulating Mouse Epidermal Growth Factor (mEGF) and on the Reproductive Function in Male Mice</title><source>J-STAGE Freely Available Titles - English</source><source>Free Full-Text Journals in Chemistry</source><creator>TOKIDA, Noriaki ; SHINODA, Ichizo ; KUROBE, Masayuki ; TATEMOTO, Yukihiro ; MORI, Masahiko ; HAYASHI, Kyozo</creator><creatorcontrib>TOKIDA, Noriaki ; SHINODA, Ichizo ; KUROBE, Masayuki ; TATEMOTO, Yukihiro ; MORI, Masahiko ; HAYASHI, Kyozo</creatorcontrib><description>Levels of mouse epidermal growth factor (mEGF) in mouse plasma were measured by a sensitive two-site enzyme immunoassay (EIA) to study whether sialoadenectomy (removal of submaxillary gland) affects the level of the factor in the circulation. mEGF levels in plasma of sialoadenectomized mice were lower than those of sham-operated (operated without removal of submaxillary gland) mice, but the difference was not remarkable. That is, the submaxillary gland is not the sole source of EGF in the mouse body. Though the reproductive ability of normal male mice and of those sialoadenectomized or sham-operated was also studied, no significant difference in fertility rate of the mated female mice was found among them. Thus the EGF in submaxillary gland seems not to play important roles in male reproductive function of the mice.</description><identifier>ISSN: 0912-0009</identifier><identifier>EISSN: 1880-5086</identifier><identifier>DOI: 10.3164/jcbn.5.221</identifier><language>eng</language><publisher>Gifu: SOCIETY FOR FREE RADICAL RESEARCH JAPAN</publisher><subject>circulation ; enzyme immunoassay ; epidermal growth factor ; fertility rate ; sialoadenectomy</subject><ispartof>Journal of Clinical Biochemistry and Nutrition, 1988, Vol.5(3), pp.221-229</ispartof><rights>The Editorial Secretariat of JCBN</rights><rights>Copyright Japan Science and Technology Agency 1988</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c451t-8a92af133d98ac48d80fc3db0d375466b3612e3d5ec13b4b42c005054e0198243</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,1876,4010,27904,27905,27906</link.rule.ids></links><search><creatorcontrib>TOKIDA, Noriaki</creatorcontrib><creatorcontrib>SHINODA, Ichizo</creatorcontrib><creatorcontrib>KUROBE, Masayuki</creatorcontrib><creatorcontrib>TATEMOTO, Yukihiro</creatorcontrib><creatorcontrib>MORI, Masahiko</creatorcontrib><creatorcontrib>HAYASHI, Kyozo</creatorcontrib><title>Effect of Sialoadenectomy on the Level of Circulating Mouse Epidermal Growth Factor (mEGF) and on the Reproductive Function in Male Mice</title><title>Journal of Clinical Biochemistry and Nutrition</title><addtitle>J. Clin. Biochem. Nutr.</addtitle><description>Levels of mouse epidermal growth factor (mEGF) in mouse plasma were measured by a sensitive two-site enzyme immunoassay (EIA) to study whether sialoadenectomy (removal of submaxillary gland) affects the level of the factor in the circulation. mEGF levels in plasma of sialoadenectomized mice were lower than those of sham-operated (operated without removal of submaxillary gland) mice, but the difference was not remarkable. That is, the submaxillary gland is not the sole source of EGF in the mouse body. Though the reproductive ability of normal male mice and of those sialoadenectomized or sham-operated was also studied, no significant difference in fertility rate of the mated female mice was found among them. Thus the EGF in submaxillary gland seems not to play important roles in male reproductive function of the mice.</description><subject>circulation</subject><subject>enzyme immunoassay</subject><subject>epidermal growth factor</subject><subject>fertility rate</subject><subject>sialoadenectomy</subject><issn>0912-0009</issn><issn>1880-5086</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><recordid>eNo9kM9qGzEQxkVIIE6aS59A0EtbWFdaSWvtsTVrp2ATSNKz0EqzscxacrVal7xBH7tynPowzAzfb_7wIfSRkimjFf-2Na2fimlZ0gs0oVKSQhBZXaIJqWlZEELqa3QzDFtCeCUqPkF_m64Dk3Do8JPTfdAWfO7D7hUHj9MG8AoO0B_1uYtm7HVy_gWvwzgAbvbOQtzpHi9j-JM2eKHzaMSfd81y8QVrb_8veYR9DHY0yR0AL0afi6w4j9e6B7x2Bj6gq073A9y951v0a9E8z--L1cPy5_z7qjBc0FRIXZe6o4zZWmrDpZWkM8y2xLKZ4FXVsoqWwKwAQ1nLW14aQgQRHAitZcnZLfp02psf-j3CkNQ2jNHnk4pyTuVM1DXL1NcTZWIYhgid2ke30_FVUaKOTquj00qo7HSGf5zg7ZD0C5xRHZMzPbyh-XiVcfYWeegsmo2OCjz7B4VeiLY</recordid><startdate>1988</startdate><enddate>1988</enddate><creator>TOKIDA, Noriaki</creator><creator>SHINODA, Ichizo</creator><creator>KUROBE, Masayuki</creator><creator>TATEMOTO, Yukihiro</creator><creator>MORI, Masahiko</creator><creator>HAYASHI, Kyozo</creator><general>SOCIETY FOR FREE RADICAL RESEARCH JAPAN</general><general>Japan Science and Technology Agency</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QP</scope><scope>7TK</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>1988</creationdate><title>Effect of Sialoadenectomy on the Level of Circulating Mouse Epidermal Growth Factor (mEGF) and on the Reproductive Function in Male Mice</title><author>TOKIDA, Noriaki ; SHINODA, Ichizo ; KUROBE, Masayuki ; TATEMOTO, Yukihiro ; MORI, Masahiko ; HAYASHI, Kyozo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c451t-8a92af133d98ac48d80fc3db0d375466b3612e3d5ec13b4b42c005054e0198243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>circulation</topic><topic>enzyme immunoassay</topic><topic>epidermal growth factor</topic><topic>fertility rate</topic><topic>sialoadenectomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>TOKIDA, Noriaki</creatorcontrib><creatorcontrib>SHINODA, Ichizo</creatorcontrib><creatorcontrib>KUROBE, Masayuki</creatorcontrib><creatorcontrib>TATEMOTO, Yukihiro</creatorcontrib><creatorcontrib>MORI, Masahiko</creatorcontrib><creatorcontrib>HAYASHI, Kyozo</creatorcontrib><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><jtitle>Journal of Clinical Biochemistry and Nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>TOKIDA, Noriaki</au><au>SHINODA, Ichizo</au><au>KUROBE, Masayuki</au><au>TATEMOTO, Yukihiro</au><au>MORI, Masahiko</au><au>HAYASHI, Kyozo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Sialoadenectomy on the Level of Circulating Mouse Epidermal Growth Factor (mEGF) and on the Reproductive Function in Male Mice</atitle><jtitle>Journal of Clinical Biochemistry and Nutrition</jtitle><addtitle>J. Clin. Biochem. Nutr.</addtitle><date>1988</date><risdate>1988</risdate><volume>5</volume><issue>3</issue><spage>221</spage><epage>229</epage><pages>221-229</pages><issn>0912-0009</issn><eissn>1880-5086</eissn><abstract>Levels of mouse epidermal growth factor (mEGF) in mouse plasma were measured by a sensitive two-site enzyme immunoassay (EIA) to study whether sialoadenectomy (removal of submaxillary gland) affects the level of the factor in the circulation. mEGF levels in plasma of sialoadenectomized mice were lower than those of sham-operated (operated without removal of submaxillary gland) mice, but the difference was not remarkable. That is, the submaxillary gland is not the sole source of EGF in the mouse body. Though the reproductive ability of normal male mice and of those sialoadenectomized or sham-operated was also studied, no significant difference in fertility rate of the mated female mice was found among them. Thus the EGF in submaxillary gland seems not to play important roles in male reproductive function of the mice.</abstract><cop>Gifu</cop><pub>SOCIETY FOR FREE RADICAL RESEARCH JAPAN</pub><doi>10.3164/jcbn.5.221</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0912-0009
ispartof Journal of Clinical Biochemistry and Nutrition, 1988, Vol.5(3), pp.221-229
issn 0912-0009
1880-5086
language eng
recordid cdi_proquest_journals_1441875993
source J-STAGE Freely Available Titles - English; Free Full-Text Journals in Chemistry
subjects circulation
enzyme immunoassay
epidermal growth factor
fertility rate
sialoadenectomy
title Effect of Sialoadenectomy on the Level of Circulating Mouse Epidermal Growth Factor (mEGF) and on the Reproductive Function in Male Mice
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T22%3A52%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20Sialoadenectomy%20on%20the%20Level%20of%20Circulating%20Mouse%20Epidermal%20Growth%20Factor%20(mEGF)%20and%20on%20the%20Reproductive%20Function%20in%20Male%20Mice&rft.jtitle=Journal%20of%20Clinical%20Biochemistry%20and%20Nutrition&rft.au=TOKIDA,%20Noriaki&rft.date=1988&rft.volume=5&rft.issue=3&rft.spage=221&rft.epage=229&rft.pages=221-229&rft.issn=0912-0009&rft.eissn=1880-5086&rft_id=info:doi/10.3164/jcbn.5.221&rft_dat=%3Cproquest_cross%3E3098776521%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c451t-8a92af133d98ac48d80fc3db0d375466b3612e3d5ec13b4b42c005054e0198243%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1441875993&rft_id=info:pmid/&rfr_iscdi=true