Iron Status and Coronary Risk in Rheumatic Heart Children

This study aimed at clarifying the relationship between iron status and atherogenic lipid profile in normal and chronic rheumatic heart as well as congenital heart defect children. The study included 31 children, 16 cases with chronic rheumatic heart disease (10 males and 6 females) and 6 with conge...

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Bibliographic Details
Published in:Journal of Clinical Biochemistry and Nutrition 1990, Vol.9(3), pp.197-203
Main Authors: ABUL-FADL, Azza M.A., AL-OKBI, Sahar Y.
Format: Article
Language:English
Subjects:
children
congenital heart
lipoproteins
rheumatic heart
serum iron
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Summary:This study aimed at clarifying the relationship between iron status and atherogenic lipid profile in normal and chronic rheumatic heart as well as congenital heart defect children. The study included 31 children, 16 cases with chronic rheumatic heart disease (10 males and 6 females) and 6 with congenital heart disease. Nine children with normal hearts were taken as the control. Serum iron and total iron binding capacity were higher in both chronic rheumatic and congenital heart disease children than in the controls; but the increase was only significant in the second case. Serum low-density lipoprotein cholesterol (LDL-ch) and high-density lipoprotein-cholesterol (HDL-ch) were not significantly changed in either disease. In relation to sex, no significant changes were noticed in iron status of chronic rheumatic heart children. Serum LDL-ch and LDL-ch to HDL-ch ratio were significantly higher in females than in males. A correlation study was also done between lipid profile and iron status.
ISSN:0912-0009
1880-5086
DOI:10.3164/jcbn.9.197