Early Skin Reaction Following 250 MeV Proton Peak Irradiation

Early skin reactions were observed on mouse legs irradiated in the spread out Bragg peak (SOBP) of a 250MeV proton beam, and the unmodified Bragg peak of that beam, or 29OkVp X-rays. The fifty percent moist desquamation doses for the proton SOBP, proton peak, and for X-rays were 29.7Gy, 24.5 Gy, and...

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Bibliographic Details
Published in:JOURNAL OF RADIATION RESEARCH 1987-06, Vol.28 (2), p.150-155
Main Authors: Tatsuzaki, H, Inada, T, Shimizu, T, Arimoto, T, Satoh, S, Akisada, M
Format: Article
Language:English
Subjects:
Animals
Dose-Response Relationship, Radiation
Female
Mice
Mice, Inbred ICR
Protons
Radiation Injuries, Experimental - pathology
Skin - radiation effects
Time Factors
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Summary:Early skin reactions were observed on mouse legs irradiated in the spread out Bragg peak (SOBP) of a 250MeV proton beam, and the unmodified Bragg peak of that beam, or 29OkVp X-rays. The fifty percent moist desquamation doses for the proton SOBP, proton peak, and for X-rays were 29.7Gy, 24.5 Gy, and 21.9Gy, respectively. The Bragg peak caused more severe early skin reactions than did SOBP.
ISSN:0449-3060
1349-9157
DOI:10.1269/jrr.28.150