Antifertility Activity of Striga orobanchioides

Four successive solvent extracts of the whole plant Striga orobanchioides have been screened for antifertility activity in albino rats. Of these the ethanolic extract was found to be most effective in causing significant anti-implantation activity. The antifertility activity was reversible on withdr...

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Bibliographic Details
Published in:Biological & pharmaceutical bulletin 1994/08/15, Vol.17(8), pp.1029-1031
Main Authors: HIREMATH, Shivayogi P., BADAMI, Shrishailappa, SWAMY, H.K.S., PATIL, Sarawati B., LONDONKAR, Ramesh L.
Format: Article
Language:English
Subjects:
Animals
anti-implantation activity
Biological and medical sciences
Contraceptives, Oral - pharmacology
Embryo Implantation - drug effects
Estrogen Antagonists - pharmacology
estrogenic activity
Estrogens - pharmacology
Female
General pharmacology
India
Medical sciences
Medicine, Ayurvedic
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plant Extracts - pharmacology
Plants, Medicinal - chemistry
Rats
Rats, Wistar
Striga orobanchioides
Uterus - drug effects
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Summary:Four successive solvent extracts of the whole plant Striga orobanchioides have been screened for antifertility activity in albino rats. Of these the ethanolic extract was found to be most effective in causing significant anti-implantation activity. The antifertility activity was reversible on withdrawal of treatment with the extract. The ethanolic extract at 200 mg/kg showed estrogenic activity. Histological studies of the uterus were carried out to confirm this estrogenic activity.
ISSN:0918-6158
1347-5215
DOI:10.1248/bpb.17.1029