Premature birth after the use of pentavalent antimonial: case report

A case is reported of a 19-year-old woman, at week 24 of gestation, with visceral leishmaniosis. She was treated with meglumine antimoniate at a dose of 850 mg/day for 20 days. There occurred premature birth on day five of treatment and the neonate died one day after birth. Considering the importanc...

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Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical 2003-07, Vol.36 (4), p.523
Main Authors: Silveira, Bruna Pinheiro, Araújo Sobrinho, José, Leite, Lacínia Freire, Sales, Maria das Neves Andrade, Gouveia, Maria do Socorro Araújo, Mathias, Renato Leal, Guedes Filho, Ricardo Amorim, Barbosa, Sônia Maria
Format: Article
Language:eng ; por
Subjects:
Abortion, Spontaneous - chemically induced
Adult
Antimony - adverse effects
Antiprotozoal Agents - adverse effects
Female
Fetal Death - chemically induced
Humans
Leishmaniasis, Visceral - diagnosis
Leishmaniasis, Visceral - drug therapy
Meglumine - adverse effects
Pregnancy
Pregnancy Complications, Parasitic - diagnosis
Pregnancy Complications, Parasitic - drug therapy
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Summary:A case is reported of a 19-year-old woman, at week 24 of gestation, with visceral leishmaniosis. She was treated with meglumine antimoniate at a dose of 850 mg/day for 20 days. There occurred premature birth on day five of treatment and the neonate died one day after birth. Considering the importance of protozoiasis in our population and the rarity of the association with pregnancy, we resolved to publish the case.
ISSN:0037-8682
1678-9849
DOI:10.1590/S0037-86822003000400016