Dermatologic lesions in patients infected with the human T-cell lymphotropic virus type 1 (HTLV-1)

Human T-cell Lymphotropic virus type I (HTLV-1) was the first human retrovirus described. Some time after its discovery a group of diseases were related to this virus, such as, adult T-cell leukemia lymphoma (ATLL), HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) and HTLV-1 assoc...

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Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical 2005-01, Vol.38 (1), p.43
Main Authors: Nobre, Vandack, Guedes, Antônio Carlos Martins, Proietti, Fernando Augusto, Stanciolli, Edel, Martins, Marina Lobato, Serufo, José Carlos, Antunes, Carlos Maurício, Grossi, Maria Aparecida, Lambertucci, José Roberto
Format: Article
Language:eng ; por
Subjects:
Dermatitis
Dermatitis - classification
Dermatitis - diagnosis
Dermatitis - virology
HTLV-I Infections - complications
Humans
Lesions
Leukemia
Lymphoma
Skin diseases
Skin Diseases, Viral - classification
Skin Diseases, Viral - diagnosis
Skin Diseases, Viral - virology
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Summary:Human T-cell Lymphotropic virus type I (HTLV-1) was the first human retrovirus described. Some time after its discovery a group of diseases were related to this virus, such as, adult T-cell leukemia lymphoma (ATLL), HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) and HTLV-1 associated uveitis (HAU). In the nineties, HTLV-1 was associated to a severe eczema of children, called infective dermatitis (ID). Since then, several other skin manifestations have been observed in HTLV-1-infected individuals, particularly in patients with ATLL or HAM/TSP. However, according to some reports, dermatologic lesions are also common in asymptomatic HTLV-1 carriers. Besides ID, all other skin lesions reported are nonspecific. The aim of this review is to outline the dermatologic manifestations reported in HTLV-1 infected patients, emphasizing the clinical and epidemiological value of these findings.
ISSN:0037-8682
1678-9849
DOI:10.1590/S0037-86822005000100009