Highly Efficient and Convenient Regeneration of NADPH for Asymmetric Reduction Using Bakers’ Yeast Cell Free Extract

An asymmetric reduction of ethyl pyruvate was carried out using bakers’ yeast cell free extract with addition of NADPH in catalytic amounts and glucose as a hydride source. The total turnover number of NADPH reached 7680. The efficiency of the cell free extract is discussed.

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Bibliographic Details
Published in:Chemistry letters 1996-12, Vol.25 (12), p.1079-1080
Main Authors: Utaka, Masanori, Yano, Tomoko, Ema, Tadashi, Sakai, Takashi
Format: Article
Language:English
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Summary:An asymmetric reduction of ethyl pyruvate was carried out using bakers’ yeast cell free extract with addition of NADPH in catalytic amounts and glucose as a hydride source. The total turnover number of NADPH reached 7680. The efficiency of the cell free extract is discussed.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.1996.1079