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PhSH-(Catalytic) KF as an Efficient Protocol for Chemoselective Ester O-Alkyl Cleavage under Non-hydrolytic Neutral Condition

Methyl esters are chemoselectively deprotected by thiophenol in presence of catalytic amount of KF in dry NMP (1-Methyl-2-pyrrolidinone) under non-hydrolytic neutral condition.

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Bibliographic Details
Published in:Chemistry letters 1998-04, Vol.27 (4), p.297-298
Main Authors: Nayak, Mirinal K, Chakraborti, Asit K
Format: Article
Language:English
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Description
Summary:Methyl esters are chemoselectively deprotected by thiophenol in presence of catalytic amount of KF in dry NMP (1-Methyl-2-pyrrolidinone) under non-hydrolytic neutral condition.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.1998.297