Biphasic Cyanation of Aryl Halides with Counter Phase Transfer Catalysts

The cyanation of aryl iodides with NaCN under heptane-water two-phase conditions is efficiently catalyzed by PdCl2{PPh2(m-C6H4SO3Na)}2 in the presence of zinc chloride and NaBH4, and gave the corresponding aryl nitriles in high yields. The biphasic cyanation had an advantage in that the aryl nitrile...

Full description

Saved in:
Bibliographic Details
Published in:Chemistry letters 1998-05, Vol.27 (5), p.425-426
Main Authors: Okano, Tamon, Kiji, Jitsuo, Toyooka, Yoshiharu
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The cyanation of aryl iodides with NaCN under heptane-water two-phase conditions is efficiently catalyzed by PdCl2{PPh2(m-C6H4SO3Na)}2 in the presence of zinc chloride and NaBH4, and gave the corresponding aryl nitriles in high yields. The biphasic cyanation had an advantage in that the aryl nitriles are easily separated from the mixtures of catalyst and reagents.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.1998.425