A Simple and Facile Chemo- and Regioselective Deprotection of Acetonides Using Silica Supported Sodium Hydrogen Sulfate as a Heterogeneous Catalyst

Silica supported sodium hydrogen sulfate (NaHSO4·SiO2) has been found to be an efficient heterogeneous catalyst for chemo- and regioselective deprotection of acetonides at room temperature to produce the corresponding diols in excellent yields.

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Bibliographic Details
Published in:Chemistry letters 2003-08, Vol.32 (8), p.734-735
Main Authors: Mahender, G, Ramu, R, Ramesh, C, Das, Biswanath
Format: Article
Language:English
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Description
Summary:Silica supported sodium hydrogen sulfate (NaHSO4·SiO2) has been found to be an efficient heterogeneous catalyst for chemo- and regioselective deprotection of acetonides at room temperature to produce the corresponding diols in excellent yields.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2003.734