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Display of Azido Glycoside on a Sensor Chip

Using 12-azidododecyl β-mannoside, we successfully immobilized azido glycoside onto a sensor chip by either the Staudinger reaction or reduction of azido group followed by condensation reaction. Specific binding of Concanavalin A to the sensor chip proved immobilization of the glycoside by either me...

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Bibliographic Details
Published in:Chemistry letters 2004-05, Vol.33 (5), p.580-581
Main Authors: Sato, Toshinori, Fujita, Sinya, Kasuya, Maria Carmelita Z, Hatanaka, Kenichi, Yamagata, Tatsuya
Format: Article
Language:English
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Summary:Using 12-azidododecyl β-mannoside, we successfully immobilized azido glycoside onto a sensor chip by either the Staudinger reaction or reduction of azido group followed by condensation reaction. Specific binding of Concanavalin A to the sensor chip proved immobilization of the glycoside by either method.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2004.580