Semicomprehensive and Semiquantitative Determination of Proteins with Mass Probes

We have designed and synthesized a series of mass-probes, which could be a model of a new tool for the semicomprehensive quantitative assays of proteins using mass spectrometry. In the system with mass-probes, the molecular weights were used as markers. We have synthesized the two probes, KMP-174 an...

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Bibliographic Details
Published in:Chemistry letters 2006-03, Vol.35 (3), p.290-291
Main Authors: Honda, Aki, Hifumi, Hiroki, Honma, Yuya, Tanji, Noriyuki, Suzuki, Yoshio, Suzuki, Koji
Format: Article
Language:English
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Summary:We have designed and synthesized a series of mass-probes, which could be a model of a new tool for the semicomprehensive quantitative assays of proteins using mass spectrometry. In the system with mass-probes, the molecular weights were used as markers. We have synthesized the two probes, KMP-174 and KMP-188, and ovalbumin (OVA) and the hen egg lysozyme (HEL) were evaluated by antibodies labeled with those probes.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2006.290