Elimination Filter for Verotoxins —Highly Adsorbing by Glycoconjugate Polymer

Glycoconjugate polymer having globotriose, which is a ligand for Verotoxins (VTs: VT1 and VT2), was immobilized to the filter paper. By flowing VTs solution through the filter paper, the elimination ability of the filter paper for VT1 and VT2 was evaluated. The globotriose-immobilizing filter effect...

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Bibliographic Details
Published in:Chemistry letters 2008-04, Vol.37 (4), p.438-439
Main Authors: Miyagawa, Atsushi, Kasuya, Maria Carmelita Z, Hatanaka, Kenichi
Format: Article
Language:English
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Summary:Glycoconjugate polymer having globotriose, which is a ligand for Verotoxins (VTs: VT1 and VT2), was immobilized to the filter paper. By flowing VTs solution through the filter paper, the elimination ability of the filter paper for VT1 and VT2 was evaluated. The globotriose-immobilizing filter effectively diluted the starting concentration of VT1 (1 μg/mL) and VT2 (1 μg/mL) to about one hundred thousandth and about one thousandth parts of the starting concentration, respectively.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2008.438