An Effective, One-Pot Synthesis of Fully Substituted Pyridines under Microwave Irradiation in the Absence of Solvent

A convenient, rapid, and environmentally benign protocol is described for the preparation of fully substituted pyridine derivatives via four‐component reactions between 2‐substituted acetophenones, aromatic aldehydes, malononitrile, and ammonium acetate under microwave irradiation with good yield an...

Full description

Saved in:
Bibliographic Details
Published in:Journal of heterocyclic chemistry 2013-11, Vol.50 (6), p.1346-1350
Main Authors: Yang, Xiao-Hui, Zhou, Yong-Hong, Zhang, Ping-Hu, Zhang, Li-Yun
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A convenient, rapid, and environmentally benign protocol is described for the preparation of fully substituted pyridine derivatives via four‐component reactions between 2‐substituted acetophenones, aromatic aldehydes, malononitrile, and ammonium acetate under microwave irradiation with good yield and without solvent.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.1035