EFFECT OF DIMETHYL SULFOXIDE PRETREATMENT ON ACTIVITIES OF LIPID PEROXIDE FORMATION, SUPERROXIDE DISMUTASE AND GLUTATHIONE PEROXIDASE IN THE MOUSE LIVER AFTER WHOLE-BODY IRRADIATION

We investigated the effects of dimethyl sulfoxide (DMSO) on radiation damage in the mouse. DMSO(i.p.0.11g/mouse)administered 30 min before exposure protected the mice from the gamma-whole body irradiation:the 30 days lethality was significantly decreased from 44% to 16%(P

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Bibliographic Details
Published in:Journal of toxicological sciences 1993/11/25, Vol.18(4), pp.239-244
Main Authors: UEDA, Takako, TOYOSHIMA, Yoshie, KUSHIHASHI, Tamio, HISHIDA, Toyohiko, YASUHARA, Hajime
Format: Article
Language:English
Subjects:
Glutathione peroxidase
Online Access:Get full text
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Description
Summary:We investigated the effects of dimethyl sulfoxide (DMSO) on radiation damage in the mouse. DMSO(i.p.0.11g/mouse)administered 30 min before exposure protected the mice from the gamma-whole body irradiation:the 30 days lethality was significantly decreased from 44% to 16%(P
ISSN:0388-1350
1880-3989
DOI:10.2131/jts.18.4_239