Postural control in restless legs syndrome with medication intervention using pramipexole

Central dopamine regulation is involved in postural control and in the pathophysiology of restless legs syndrome (RLS) and Parkinson’s disease (PD). Postural control abnormalities have been detected in PD, but there are no earlier studies with regard to RLS and postural control. Computerized force p...

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Bibliographic Details
Published in:Neurological sciences 2014-02, Vol.35 (2), p.199-204
Main Authors: Ahlgrén-Rimpiläinen, Aulikki, Lauerma, Hannu, Kähkönen, Seppo, Aalto, Heikki, Tuisku, Katinka, Holi, Matti, Pyykkö, Ilmari, Rimpiläinen, Ilpo
Format: Article
Language:English
Subjects:
Adult
Benzothiazoles - therapeutic use
Biomechanical Phenomena
Dopamine Agonists - therapeutic use
Female
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Motion
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Original Article
Posture
Psychiatry
Psychomotor Agitation - diagnosis
Psychomotor Agitation - drug therapy
Psychomotor Agitation - etiology
Restless Legs Syndrome - complications
Restless Legs Syndrome - diagnosis
Restless Legs Syndrome - drug therapy
Severity of Illness Index
Time Factors
Treatment Outcome
Vision, Ocular
Visual Perception
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Summary:Central dopamine regulation is involved in postural control and in the pathophysiology of restless legs syndrome (RLS) and Parkinson’s disease (PD). Postural control abnormalities have been detected in PD, but there are no earlier studies with regard to RLS and postural control. Computerized force platform posturography was applied to measure the shift and the velocity (CPFV) of center point of forces (CPF) with eyes open (EO) and eyes closed (EC) in controls ( n  = 12) and prior and after a single day intervention with pramipexole in RLS subjects ( n  = 12). CPFV (EO) was significantly lower in the RLS group ( p  
ISSN:1590-1874
1590-3478
DOI:10.1007/s10072-013-1478-6