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Deregulation of Feedback Inhibition of Phosphoenolpyruvate Carboxylase for Improved Lysine Production in Corynebacterium glutamicum
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Published in: | Applied and Environmental Microbiology 2014-02, Vol.80 (4), p.1388-1393 |
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creator | Chen, Zhen Bommareddy, Rajesh Reddy Frank, Doinita Rappert, Sugima Zeng, An-Ping |
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Print ISSN:
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</description><identifier>ISSN: 0099-2240</identifier><identifier>EISSN: 1098-5336</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AEM.03535-13</identifier><identifier>PMID: 24334667</identifier><identifier>CODEN: AEMIDF</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>Aspartic Acid - metabolism ; Bacteria ; Biotechnology ; Carbon Isotopes - metabolism ; Corynebacterium glutamicum ; Corynebacterium glutamicum - genetics ; Corynebacterium glutamicum - metabolism ; Enzyme Inhibitors - metabolism ; Feedback ; Gene Expression Regulation, Bacterial ; Gene Expression Regulation, Enzymologic ; Isotope Labeling ; Lysine - biosynthesis ; Malates - metabolism ; Metabolic Engineering - methods ; Metabolic Flux Analysis ; Metabolism ; Mutant Proteins - genetics ; Mutant Proteins - metabolism ; Mutation ; NADP - metabolism ; Phosphates ; Phosphoenolpyruvate Carboxylase - genetics ; Phosphoenolpyruvate Carboxylase - metabolism ; Point Mutation ; Proteins</subject><ispartof>Applied and Environmental Microbiology, 2014-02, Vol.80 (4), p.1388-1393</ispartof><rights>Copyright American Society for Microbiology Feb 2014</rights><rights>Copyright © 2014, American Society for Microbiology. All Rights Reserved. 2014 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c537t-6db1a0f0bb952b92f5966dda86b69a6567196950aa2dd9dc3650742e6aa3d4573</citedby><cites>FETCH-LOGICAL-c537t-6db1a0f0bb952b92f5966dda86b69a6567196950aa2dd9dc3650742e6aa3d4573</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911046/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911046/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,3188,3189,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24334667$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chen, Zhen</creatorcontrib><creatorcontrib>Bommareddy, Rajesh Reddy</creatorcontrib><creatorcontrib>Frank, Doinita</creatorcontrib><creatorcontrib>Rappert, Sugima</creatorcontrib><creatorcontrib>Zeng, An-Ping</creatorcontrib><title>Deregulation of Feedback Inhibition of Phosphoenolpyruvate Carboxylase for Improved Lysine Production in Corynebacterium glutamicum</title><title>Applied and Environmental Microbiology</title><addtitle>Appl Environ Microbiol</addtitle><description>Classifications
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</description><subject>Aspartic Acid - metabolism</subject><subject>Bacteria</subject><subject>Biotechnology</subject><subject>Carbon Isotopes - metabolism</subject><subject>Corynebacterium glutamicum</subject><subject>Corynebacterium glutamicum - genetics</subject><subject>Corynebacterium glutamicum - metabolism</subject><subject>Enzyme Inhibitors - metabolism</subject><subject>Feedback</subject><subject>Gene Expression Regulation, Bacterial</subject><subject>Gene Expression Regulation, Enzymologic</subject><subject>Isotope Labeling</subject><subject>Lysine - biosynthesis</subject><subject>Malates - metabolism</subject><subject>Metabolic Engineering - methods</subject><subject>Metabolic Flux Analysis</subject><subject>Metabolism</subject><subject>Mutant Proteins - genetics</subject><subject>Mutant Proteins - metabolism</subject><subject>Mutation</subject><subject>NADP - metabolism</subject><subject>Phosphates</subject><subject>Phosphoenolpyruvate Carboxylase - genetics</subject><subject>Phosphoenolpyruvate Carboxylase - metabolism</subject><subject>Point Mutation</subject><subject>Proteins</subject><issn>0099-2240</issn><issn>1098-5336</issn><issn>1098-6596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNqFkr1v1DAYhyMEokdhY0ZGLAyk2PFH7AWpOlo46RAdYLac-M3FJYmDnRxk5h_H12srYGGy9PrRo_fjl2XPCT4jpJBvzy8-nWHKKc8JfZCtCFYy55SKh9kKY6XyomD4JHsS4zXGmGEhH2cnBaOUCVGusl_vIcBu7szk_IB8gy4BbGXqb2gztK5yd-Wr1sex9TD4blzCvDcToLUJlf-5dCYCanxAm34Mfg8WbZfoBkBXwdu5vjG4Aa19WAZI6gmCm3u06-bJ9K6e-6fZo8Z0EZ7dvqfZ18uLL-uP-fbzh836fJvXnJZTLmxFDG5wVSleVKpouBLCWiNFJZQRXJRECcWxMYW1ytZUcFyyAoQx1DJe0tPs3dE7zlUPtoZhCqbTY3C9CYv2xum_fwbX6p3fa6oIwUwkwetbQfDfZ4iT7l2soevMAH6OmnCcNp8awf9HmaKlUoWkCX31D3rt5zCkTRwoIZiUQiXqzZGqg48xQHPfN8H6EASdgqBvgqDJQfriz1nv4bvLJ-DlEWjdrv3hAmgTe22g1xJrlhRS0t-wO7wT</recordid><startdate>20140201</startdate><enddate>20140201</enddate><creator>Chen, Zhen</creator><creator>Bommareddy, Rajesh Reddy</creator><creator>Frank, Doinita</creator><creator>Rappert, Sugima</creator><creator>Zeng, An-Ping</creator><general>American Society for Microbiology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QO</scope><scope>7SN</scope><scope>7SS</scope><scope>7ST</scope><scope>7T7</scope><scope>7TM</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>SOI</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20140201</creationdate><title>Deregulation of Feedback Inhibition of Phosphoenolpyruvate Carboxylase for Improved Lysine Production in Corynebacterium glutamicum</title><author>Chen, Zhen ; 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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>24334667</pmid><doi>10.1128/AEM.03535-13</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | American Society for Microbiology Journals; PubMed Central |
subjects | Aspartic Acid - metabolism Bacteria Biotechnology Carbon Isotopes - metabolism Corynebacterium glutamicum Corynebacterium glutamicum - genetics Corynebacterium glutamicum - metabolism Enzyme Inhibitors - metabolism Feedback Gene Expression Regulation, Bacterial Gene Expression Regulation, Enzymologic Isotope Labeling Lysine - biosynthesis Malates - metabolism Metabolic Engineering - methods Metabolic Flux Analysis Metabolism Mutant Proteins - genetics Mutant Proteins - metabolism Mutation NADP - metabolism Phosphates Phosphoenolpyruvate Carboxylase - genetics Phosphoenolpyruvate Carboxylase - metabolism Point Mutation Proteins |
title | Deregulation of Feedback Inhibition of Phosphoenolpyruvate Carboxylase for Improved Lysine Production in Corynebacterium glutamicum |
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