A Genome Wide Approach to Identify Genetic Determinants of Asthma Traits Related to Airway Function in Two Populations of African Descent

Using the Illumina HumanHap650Y BeadChip, we genotyped 655,352 single nucleotide polymorphisms (SNPs) on two asthmatic populations of African ancestry: 998 case-controls in Baltimore-Washington D.C. and 977 family based subjects in Barbados, among whom 131 and 215 asthmatics, respectively, had compl...

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2009-02, Vol.123 (2), p.S148-S148
Main Authors: Tsai, Y.J, Mathias, R, Grant, A, Rafaels, N, Hand, T, Togias, A, Hansel, N, Diette, G, Adkinson, N.F, Liu, M.C., MD, Faruque, M, Watson, H, Scott, A, Ruczinski, I, Dunston, G, Beaty, T, Barnes, K.C
Format: Article
Language:English
Subjects:
Allergy and Immunology
Genes
Genomes
Genomics
Online Access:Get full text
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Summary:Using the Illumina HumanHap650Y BeadChip, we genotyped 655,352 single nucleotide polymorphisms (SNPs) on two asthmatic populations of African ancestry: 998 case-controls in Baltimore-Washington D.C. and 977 family based subjects in Barbados, among whom 131 and 215 asthmatics, respectively, had complete lung function data.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2008.12.555