Characterization of Allergic Patients' Serum IgE Composition by Facilitated Allergen Presentation

Complex-formation between IgE, allergen and cell-surface IgE-receptors (Fc[varepsilon]RI, CD23) is fundamental for the immediate allergic-response (activation of mast-cells/basophils), and activation of allergen-specific T-cells through Facilitated Antigen Presentation (FAP).

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2009-02, Vol.123 (2), p.S126-S126
Main Authors: Willumsen, N, Holm, J, Christensen, L.H, Würtzen, P.A, Lund, K
Format: Article
Language:English
Subjects:
Allergies
Allergy and Immunology
Medical research
Online Access:Get full text
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Description
Summary:Complex-formation between IgE, allergen and cell-surface IgE-receptors (Fc[varepsilon]RI, CD23) is fundamental for the immediate allergic-response (activation of mast-cells/basophils), and activation of allergen-specific T-cells through Facilitated Antigen Presentation (FAP).
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2008.12.464