The dependency of early (EPR) and late phase (LPR) asthmatic reactions on eosinophils and effector functions such as degranulation

The data show that eosinophil activities are critical for allergen-induced bronchoconstriction and suggest that eosinophil effector function(s) such as immunoregulation of the pulmonary micro environment is critical for these inflammatory responses.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2005-02, Vol.115 (2), p.S190-S190
Main Authors: Cieslewicz, G., Ochkur, S.I., Lee, J.J., Lee, N.A.
Format: Article
Language:English
Subjects:
Airway management
Allergies
Rodents
Online Access:Get full text
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Description
Summary:The data show that eosinophil activities are critical for allergen-induced bronchoconstriction and suggest that eosinophil effector function(s) such as immunoregulation of the pulmonary micro environment is critical for these inflammatory responses.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2004.12.773