Effect of anti-IgE therapy on atopic eczema symptoms in patients with asthma

The high-affinity receptor for IgE on myeloid dendritic cells has been shown to play a major role in AD. Since anti-IgE antibodies can reduce circulating free IgE and down regulate FcεRI expression, we examined the effect of anti-IgE therapy (omalizumab) on AD.

Saved in:
Bibliographic Details
Published in:Journal of allergy and clinical immunology 2005-02, Vol.115 (2), p.S104-S104
Main Authors: Vigo, P.G., Hussain, I., Girgis, K.R., Pfuetze, B.L., Critchlow, M.E., Fisher, J.
Format: Article
Language:English
Subjects:
Allergies
Asthma
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The high-affinity receptor for IgE on myeloid dendritic cells has been shown to play a major role in AD. Since anti-IgE antibodies can reduce circulating free IgE and down regulate FcεRI expression, we examined the effect of anti-IgE therapy (omalizumab) on AD.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2004.12.430