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Suppression of established experimental asthma by Toll-like receptor 7 activation

Subcutaneous R-848 application reversed established allergic asthma by suppressing airway eosinophilia, inflammation of the airway mucosa, OVA-specific IgE production and normalizing airway responsiveness.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2005-02, Vol.115 (2), p.S64-S64
Main Authors: Sel, S., Wegmann, M., Garn, H., Alber, G., Renz, H.
Format: Article
Language:English
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Description
Summary:Subcutaneous R-848 application reversed established allergic asthma by suppressing airway eosinophilia, inflammation of the airway mucosa, OVA-specific IgE production and normalizing airway responsiveness.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2004.12.269