IgE Crosslinking on Human Plasmacytoid Dendritic Cells (pDCs) Interferes with CD4 T cell Alloproliferation

IgE crosslinking on human pDCs by exposure to anti-IgE in vitro results in a significant impairment in the capacity of influenza-exposed pDCs to drive CD4 T lymphocyte proliferation.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2010-02, Vol.125 (2), p.AB228-AB228
Main Authors: Gill, M.A, Dong, C, Dougherty, I, Gruchalla, R
Format: Article
Language:English
Subjects:
Allergy and Immunology
Cell growth
Influenza
Lymphocytes
Online Access:Get full text
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Description
Summary:IgE crosslinking on human pDCs by exposure to anti-IgE in vitro results in a significant impairment in the capacity of influenza-exposed pDCs to drive CD4 T lymphocyte proliferation.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2009.12.890