Coordinate Regulation of Eosinophil Development by a Transcriptional Network and IL-5

Eosinophil maturation from progenitor to effector cell is orchestrated by the early induction of a number of transcription factors, while expression of genes associated with effector function peaked days later.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2010-02, Vol.125 (2), p.AB108-AB108
Main Authors: Fulkerson, P.C, McBride, M, Rothenberg, M.E
Format: Article
Language:English
Subjects:
Allergy and Immunology
Gene expression
Medical research
Transcription factors
Online Access:Get full text
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Description
Summary:Eosinophil maturation from progenitor to effector cell is orchestrated by the early induction of a number of transcription factors, while expression of genes associated with effector function peaked days later.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2009.12.427