Human Th2 cells Produce IFN-gamma Due to Hyper-Expression of T-bet

METHODS: Since cord blood naive CD4+ T cells developed into representative Th2 cells, the expression of Th1/Th2-specific transcription factors in peripheral and cord blood CD4+ T cells was comparatively analyzed by means of Western blotting and restriction enzyme accessibility assay.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2010-02, Vol.125 (2), p.AB144-AB144
Main Authors: Kaminuma, O, Kitamura, N, Mori, A, Nemoto, S, Tatsumi, H, Miyoshi, H, Miyatake, S, Kitamura, F, Yamaoka, K, Hiroi, T
Format: Article
Language:English
Subjects:
Allergy and Immunology
Genes
Lymphocytes
Transcription factors
Online Access:Get full text
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Description
Summary:METHODS: Since cord blood naive CD4+ T cells developed into representative Th2 cells, the expression of Th1/Th2-specific transcription factors in peripheral and cord blood CD4+ T cells was comparatively analyzed by means of Western blotting and restriction enzyme accessibility assay.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2009.12.565